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FDA reclassifies 14 peptides to Category 1: BPC-157, CJC-1295, ipamorelin now legally compoundableTaurine deficiency identified as driver of aging in landmark Science study — supplementation extends lifespan 12%Epigenetic clocks now available direct-to-consumer: how to measure your biological age in 2026Urolithin A Phase III: mitophagy supplement improves muscle endurance 12% in adults over 65VO2max emerges as strongest single predictor of all-cause mortality in 750,000-person meta-analysisFisetin senolytic trial at Mayo Clinic: strawberry compound clears zombie cells in Phase IPartial Yamanaka factor reprogramming passes 18-month safety milestone in primate studiesFirst large-scale NMN trial: 1,200 participants show 2.4-year reduction in epigenetic ageDeep sleep decline after 40 accelerates Alzheimer's pathology — new interventions restore slow-wave activityAlpha-ketoglutarate reduces biological age 8 years in open-label trial of 42 adultsFDA reclassifies 14 peptides to Category 1: BPC-157, CJC-1295, ipamorelin now legally compoundableTaurine deficiency identified as driver of aging in landmark Science study — supplementation extends lifespan 12%Epigenetic clocks now available direct-to-consumer: how to measure your biological age in 2026Urolithin A Phase III: mitophagy supplement improves muscle endurance 12% in adults over 65VO2max emerges as strongest single predictor of all-cause mortality in 750,000-person meta-analysisFisetin senolytic trial at Mayo Clinic: strawberry compound clears zombie cells in Phase IPartial Yamanaka factor reprogramming passes 18-month safety milestone in primate studiesFirst large-scale NMN trial: 1,200 participants show 2.4-year reduction in epigenetic ageDeep sleep decline after 40 accelerates Alzheimer's pathology — new interventions restore slow-wave activityAlpha-ketoglutarate reduces biological age 8 years in open-label trial of 42 adults
Volume 12, Issue 4 — April 2026 | Special Issue: Peptides, Senolytics & the New Longevity Toolbox

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Brain neural network visualization
News Feature

NAD+ Supplementation Shows Promise for Slowing Brain Aging and Neurodegeneration

Multi-center study reveals that boosting NAD+ protects neurons through enhanced DNA repair and improved mitochondrial quality control via mitophagy

February 14, 202610 min read
Molecular biology research visualization
News Feature

Dog Aging Project Confirms Rapamycin Extends Healthy Lifespan in Companion Animals

TRIAD interim results from 580 dogs show low-dose rapamycin improves cardiac function, reduces cancer incidence, and extends median lifespan by 15%

March 16, 202611 min read
Neuroscience and cognitive aging research
News Feature

Klotho Protein Injection Reverses Cognitive Decline in Aged Primates and Enters Human Trials

A single low-dose injection of the longevity-associated protein klotho restores synaptic plasticity and spatial memory in aged macaques, with Phase I human trial now enrolling

January 10, 202611 min read

News & Commentary

Person stretching in morning light, representing vitality and energy
News Feature

What Is NAD+ and Why You Have No Energy After 35

March 18, 2026 · 12 min read

Brain neural network visualization
Molecular biology research visualization
Neuroscience and cognitive aging research
Stem cell culture in a laboratory petri dish with visible fluorescent markers
Editorial

The NAD+ Revolution: From Bench to Bedside

After a decade of promising preclinical research, NAD+ biology is finally yielding clinical results. The convergence of epigenetic clocks, large-scale trials, and pharmaceutical CD38 inhibitors marks a turning point in longevity medicine. We examine what comes next.

By the Editors of Longevity News · March 2026

Trending

  1. 01FDA reclassifies 14 peptides to Category 1: BPC-157, CJC-1295, ipamorelin now legally compoundable
  2. 02Taurine deficiency identified as driver of aging in landmark Science study — supplementation extends lifespan 12%
  3. 03Epigenetic clocks now available direct-to-consumer: how to measure your biological age in 2026
  4. 04Urolithin A Phase III: mitophagy supplement improves muscle endurance 12% in adults over 65
  5. 05VO2max emerges as strongest single predictor of all-cause mortality in 750,000-person meta-analysis
  6. 06Fisetin senolytic trial at Mayo Clinic: strawberry compound clears zombie cells in Phase I
  7. 07Partial Yamanaka factor reprogramming passes 18-month safety milestone in primate studies
  8. 08First large-scale NMN trial: 1,200 participants show 2.4-year reduction in epigenetic age
  9. 09Deep sleep decline after 40 accelerates Alzheimer's pathology — new interventions restore slow-wave activity
  10. 10Alpha-ketoglutarate reduces biological age 8 years in open-label trial of 42 adults

Most Read

Molecular biology research visualization
News Feature

Dog Aging Project Confirms Rapamycin Extends Healthy Lifespan in Companion Animals

March 16, 2026

Neuroscience and cognitive aging research
News Feature

Klotho Protein Injection Reverses Cognitive Decline in Aged Primates and Enters Human Trials

January 10, 2026

Stem cell culture in a laboratory petri dish with visible fluorescent markers
News Feature

Epigenetic Reprogramming Without Cancer: Partial Yamanaka Factors Reach Safety Milestone

February 20, 2026

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Impact Factor68.2
5-Year IF72.1
Immediacy Index14.8
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CiteScore98.4