Clinical Trial
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Research Articles
156
Clinical Trials Tracked
423
Reviews Published
68.2
Impact Factor
Featured Research
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Senolytic Drugs Extend Healthspan in First Large Human Trial
Dasatinib plus quercetin clears senescent cells and improves physical function in adults over 65, marking a milestone for the senolytic field
TAME Trial Interim Data Suggest Metformin Slows Multi-Morbidity Onset in Aging Adults
The first FDA-approved anti-aging clinical trial reports that metformin delays the composite onset of cardiovascular disease, cancer, cognitive decline, and mortality
Thymus Regeneration Protocol Reverses Immune Aging and Epigenetic Age in Humans
TRIIM-X trial demonstrates that a growth hormone–based regimen regenerates thymic tissue, restores naive T cell production, and reverses epigenetic age by 4.6 years in adults aged 50–72
News & Commentary
First Large-Scale NMN Trial Shows Significant Improvement in Biological Age Markers
March 8, 2026 · 14 min read
Senolytic Drugs Extend Healthspan in First Large Human Trial
March 19, 2026 · 13 min read
TAME Trial Interim Data Suggest Metformin Slows Multi-Morbidity Onset in Aging Adults
March 3, 2026 · 12 min read
Thymus Regeneration Protocol Reverses Immune Aging and Epigenetic Age in Humans
February 16, 2026 · 12 min read
Urolithin A Activates Mitophagy and Improves Muscle Function in Aging Adults
April 10, 2026 · 13 min read
Alpha-Ketoglutarate: The Metabolite That Reduces Biological Age by 8 Years
April 5, 2026 · 12 min read
The NAD+ Revolution: From Bench to Bedside
After a decade of promising preclinical research, NAD+ biology is finally yielding clinical results. The convergence of epigenetic clocks, large-scale trials, and pharmaceutical CD38 inhibitors marks a turning point in longevity medicine. We examine what comes next.
By the Editors of Longevity News · March 2026
Trending
- 01FDA reclassifies 14 peptides to Category 1: BPC-157, CJC-1295, ipamorelin now legally compoundable
- 02Taurine deficiency identified as driver of aging in landmark Science study — supplementation extends lifespan 12%
- 03Epigenetic clocks now available direct-to-consumer: how to measure your biological age in 2026
- 04Urolithin A Phase III: mitophagy supplement improves muscle endurance 12% in adults over 65
- 05VO2max emerges as strongest single predictor of all-cause mortality in 750,000-person meta-analysis
- 06Fisetin senolytic trial at Mayo Clinic: strawberry compound clears zombie cells in Phase I
- 07Partial Yamanaka factor reprogramming passes 18-month safety milestone in primate studies
- 08First large-scale NMN trial: 1,200 participants show 2.4-year reduction in epigenetic age
- 09Deep sleep decline after 40 accelerates Alzheimer's pathology — new interventions restore slow-wave activity
- 10Alpha-ketoglutarate reduces biological age 8 years in open-label trial of 42 adults
Most Read
TAME Trial Interim Data Suggest Metformin Slows Multi-Morbidity Onset in Aging Adults
March 3, 2026
Thymus Regeneration Protocol Reverses Immune Aging and Epigenetic Age in Humans
February 16, 2026
Urolithin A Activates Mitophagy and Improves Muscle Function in Aging Adults
April 10, 2026
Alpha-Ketoglutarate: The Metabolite That Reduces Biological Age by 8 Years
April 5, 2026
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